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LipTx™ Formulation Kits

LipTx™ Formulation Kits provide pre-optimized, four-component lipid mixtures that enable efficient RNA encapsulation without requiring specialized formulation expertise. Every kit delivers a precisely measured blend of a LipTx™ proprietary ionizable lipid, helper lipid, cholesterol, and a conjugated PEG-lipid, streamlined to ensure reproducible particle size and batch-to-batch consistency.

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Kit Advantages

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  • Ready-to-Use Blends: Eliminates complex optimization steps by providing pre-formulated lipid matrices for rapid in vitro and in vivo screening.

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  • Broad Payload Compatibility: Supports quick encapsulation of mRNA, saRNA, circRNA, siRNA, and CRISPR-Cas gene-editing payloads.

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  • Flexible Scaling: Available in stock 2 mL, 5 mL, and 10 mL volumes to seamlessly match your research throughput.

Master Selection & Formulation Matrix

Product Name
Target Applications
Lipid Architecture
Technical Focus
LipTx™ NV1-002 Formulation Kit
  • - General-purpose LNP screening
  • - mRNA vaccine formulation
  • - Academic & preclinical research
Biodegradable ionizable amino-lipid with a standard tail configuration.
Validated baseline platform for nucleic acid encapsulation and endosomal escape.
LipTx™ NV1-012 Formulation Kit
  • - mRNA therapeutic development
  • - Protein replacement therapy programs
Ionizable amino-lipid with extended hydrophobic tail variations and ester linkages.
Tuned lipophilicity to enhance membrane fusion and efficient cytosolic payload release.
LipTx™ NV2-004 Formulation Kit
  • - siRNA delivery
  • - Repeat-dosing regimens
  • - Extended formulation shelf life
Biodegradable tail combined with an unsaturated hydrocarbon tail via an ether linkage.
Maximized hydrolytic stability and long-term lipid robustness without compromising delivery performance.
LipTx™ NV2-011 Formulation Kit
  • - High-throughput lipid screening
  • - Fast formulation iterations
  • - CRISPR-Cas screening systems
Biodegradable tail paired with a saturated hydrocarbon tail in a single-chain design.
Streamlined lipid architecture optimized specifically for rapid formulation turnaround.
LipTx™ NV3-001 Formulation Kit
  • - Gene therapy
  • - In vivo genome editing
  • - Ex vivo cell therapies (e.g., CAR-T)
Orthogonally oriented ionizable centers linked through biodegradable ester bonds and unsaturated carbon tails.
Increased lipid fluidity within the LNP bilayer to maximize efficient membrane fusion.
LipTx™ NV3-006 Formulation Kit
  • - Scale-up development programs
  • - Clinical translation workflows
  • - High-stability platforms
Orthogonally oriented ionizable center architecture paired with saturated carbon tails.
Prioritizes structural particle stability over fluidity to maintain highly consistent particle characteristics during scale-up.

LipTx™ NV1-002 Kit

LipTx™ NV2-011 Kit

LipTx™ NV1-012 Kit

LipTx™ NV3-001 Kit

LipTx™ NV2-004 Kit

LipTx™ NV3-006 Kit

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