
LipTx™ Ionizable Lipids
Our LipTx™ ionizable lipid portfolio offers a high-purity, proprietary platform engineered to advance RNA therapeutic development from discovery through to manufacturing. Designed to stay neutral at physiological pH and protonate in acidic environments, these novel lipids drive high encapsulation efficiency (>90%) and potent endosomal release across diverse nucleic acid cargoes.
Product Series Overview
-
The NV1 Series (High-Efficiency & Fusion): Ester-linked configurations featuring NV1-002 for standard baseline encapsulation and NV1-012 for enhanced membrane fusion.
-
The NV2 Series (Hybrid Tails & Stability): Combines biodegradable and hydrocarbon tails, featuring ether-linked NV2-004 for improved hydrolytic stability and saturated NV2-011 for rapid screening.
-
The NV3 Series (Orthogonal Centers): Employs orthogonally oriented ionizable centers, featuring unsaturated NV3-001 for lipid fluidity and saturated NV3-006 for optimized formulation stability.

