Controlled Biodegradability

Tailored cleavability of NeoVac’s lipids allow for improved safety and activity

Tuning biodegradability by linkers of different cleavability

High

Medium

Low

Different chemical motifs are applied for adjusting stability and responsiveness

Applicable to lipids with different molecular architecture

Branched, custom cleavability

Double-branched, staggered cleavability

Membrane spanning archea inspired

Head-to-head linked Dendrimer inspired

NeoVac Lipid Differentiation

Stability and biodegradability must be balanced for different types of pharmaceutical applications.

Combining tailored biodegradability and immunogenicity allows application of NeoVac lipids for many different types of pharmaceutical products