TUNABLE IMMUNOGENICITY

NeoVac’s low-immunogenic LNPs are optimal for indications requiring repeated injections

High

Medium

Low

Immunogenicity Spectrum

Indicated for high immunogenic indications (e.g. vaccines)

Indicated for multiple/repeat injections (e.g., oncology, protein replacement)

NeoVac Lipid Differentiation

High innate immunogenicity limits conventional ionizable lipids from use in repeat dosing or autoimmune settings

NeoVac lipids provide precise control over innate immunogenicity, allowing generation of immune-silent LNPs with enhanced activity and organ selectivity

Cytokines in mice Vaccinated with mRNA-LNPs

Organ & Cell Specific Targeting